Identifying a Reviewing IRB

When submitting a request for reliance, the submitter requests a specific Reviewing IRB on the request form.

Once the request has been submitted, the Overall PI’s home institution first reviews the request to determine whether the study is eligible for reliance; if so, that institution is then given the first option to serve as the Reviewing IRB. If the Overall PI's home institution declines or is unable to serve as the Reviewing IRB, that institution’s Reliance POC or Reliance POC Backup(s) have the responsibility to propose a Reviewing IRB in the System, and may take the investigator’s request into consideration in doing so.

After an institution indicates willingness to be the proposed Reviewing IRB, the Reviewing IRB will be able to confirm or deny the request, at which point a determination letter will be generated either documenting that reliance has been reached, or that reliance has not been reached.