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  1. SMART IRB Support Center
  2. Reliance System

Reliance System

Login and Registration

  • Login Instructions: Creating a SMART IRB Account
  • Logging in to the Reliance System
  • Introduction to the Reliance System
  • Login Issues: I received a login failed message.
  • Which login options should I choose when I create my account?
  • Technical Difficulties

Institution Management

  • Changing Point of Contact(s)
  • Submitting and Updating Institutional Profile
  • How can I change/correct information on the Participating Institutions page?
  • How can I obtain a copy of my institution's signed Joinder Agreement?

Reliance Requests

  • Reliance Request Creation
  • Editing Reliance Requests
  • Identifying a Reviewing IRB
  • Adding Additional Sites
  • Adding Research Personnel
  • Institution not listed in Reliance System
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User Management

  • Dashboard
  • Site Admin Role
  • Participating Institution contact information
  • Designating User Role
  • Group Emails
  • Permissions

Legacy Requests

  • Documenting SMART IRB reliance arrangements made prior to launch of the Reliance System
  • ORS Requests and In Progress Requests
  • Administrative Withdrawal and Site Removal
  • Do previous requests from Online Reliance System (ORS) carry over to the Reliance System?
  • Can I re-open a request that is administratively withdrawn?

Reliance System Patchnotes

  • Reliance System: Updates and Work in Progress (June 29, 2026)
  • 02.24.26 Patch Release Notes
  • 02.04.26 Patch Release Notes
  • 01.12.26 Patch Release Notes
  • 12.11.25 Patch Release Notes
SMART IRB Support Center